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Lewy bodies

British

/ ˈluːɪ /

plural noun

abnormal proteins that occur in the nerve cells of the cerebral cortex and the basal ganglia, causing Parkinson's disease and dementia

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of Lewy bodies

C20: named after F. H. Lewy (1885–1950), German neurologist

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

"Moving forward, we plan to explore the molecular pathways disrupted by Lewy bodies to identify mechanisms that may be protective."

From Science Daily • Apr. 16, 2024

Some tests will also look for potential biomarkers for vascular and frontotemporal dementia, and dementia with Lewy bodies.

From BBC • Apr. 4, 2024

Those aggregations closely resembled structures called Lewy bodies that are a signature of Parkinson’s in human brains.

From Science Magazine • May 4, 2023

Lewy bodies spread as pieces of these amyloids break away and seed the formation of new Lewy bodies in neighboring neurons.

From Salon • Apr. 24, 2023

Another is Lewy body dementia, in which small clusters of α-synuclein called Lewy bodies build up in the brain, disrupting movement and cognition.

From Scientific American • Jan. 24, 2023

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023