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nondisjunction

American  
[non-dis-juhngk-shuhn] / ˌnɒn dɪsˈdʒʌŋk ʃən /

noun

Biology.
  1. the failure of chromosomes to separate and segregate into daughter cells at division.


nondisjunction British  
/ ˌnɒndɪsˈdʒʌŋkʃən /

noun

  1. the failure of paired homologous chromosomes to move to opposite poles of the cell during meiosis

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of nondisjunction

First recorded in 1910–15; non- + disjunction

Vocabulary lists containing nondisjunction

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Nondisjunction occurs when a pair of homologous chromosomes fails to segregate during meiosis II resulting in the formation of gametes containing n+1, n-1, or n numbers of chromosomes.

From Textbooks • Jun. 9, 2022

Nondisjunction occurs due to the inability of sister chromatids to separate during meiosis II, resulting in the formation of gametes containing n+1 and n-1 chromosomes.

From Textbooks • Jun. 9, 2022

Nondisjunction only occurs when homologous chromosomes do not separate during meiosis I, resulting in the formation of gametes containing n+1 and n-1 chromosomes.

From Textbooks • Jun. 9, 2022

Nondisjunction only occurs when sister chromatids do not separate in meiosis II, resulting in the formation of gametes containing n+1 and n-1 chromosomes.

From Textbooks • Jun. 9, 2022

Nondisjunction, the failure of homologous chromosomes to separate during meiosis, can lead to chromosome number disorders.

From Textbooks • Jan. 1, 2018

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