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spironolactone

American  
[spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh-] / ˌspaɪ rə noʊˈlæk toʊn, spaɪˌroʊ-, -ˌrɒn ə- /

noun

Pharmacology.

  1. a steroid, C 2 4 H 3 2 O 4 S, used in combination with other drugs as a diuretic and antihypertensive.

spironolactone British  
/ ˌspaɪrənəʊˈlæktəʊn /

noun

  1. a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of spironolactone

1955–60; alteration of spirolactone; see spiro- 2, lactone

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Spironolactone, an oral medication that blocks certain hormones in the body, is sometimes recommended for severe hormonal acne in women.

From Seattle Times • Dec. 18, 2023

Spironolactone works well for some people in achieving some of their goals.

From Slate • Jun. 10, 2019

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.