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[ak-ruh-meg-uh-lee] /ˌæk rəˈmɛg ə li/
noun, Pathology.
a chronic disease characterized by enlargement of the bones of the head, the soft parts of the feet and hands, and sometimes other structures, due to excessive secretion of growth hormone by the pituitary gland.
Origin of acromegaly
1885-90; < French acromégalie < New Latin acromegalia. See acro-, -megaly
Related forms
[ak-roh-muh-gal-ik] /ˌæk roʊ məˈgæl ɪk/ (Show IPA),
pseudoacromegaly, noun Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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Examples from the Web for acromegaly
Historical Examples
  • Not rarely does it happen that acromegaly attacks the side most deficient in nerve supply.

    Degeneracy Eugene S. Talbot
  • Hypertrophy of the gland is directly associated with certain diseases, such as giantism and acromegaly.

    The Mystery of Space Robert T. Browne
  • Indeed, as Marie has said, giantism is acromegaly occurring during the period of adolescence.

    Degeneracy Eugene S. Talbot
  • acromegaly is characterised by abnormal growth, chiefly in the bones of the head, face, and extremities.

    Degeneracy Eugene S. Talbot
  • In this case also the resulting ductless gland is still of functional importance, for disease of it is associated with acromegaly.

    The Origin of Vertebrates Walter Holbrook Gaskell
British Dictionary definitions for acromegaly


a chronic disease characterized by enlargement of the bones of the head, hands, and feet, and swelling and enlargement of soft tissue, esp the tongue. It is caused by excessive secretion of growth hormone by the pituitary gland Compare gigantism
Derived Forms
acromegalic (ˌækrəʊmɪˈɡælɪk) adjective, noun
Word Origin
C19: from French acromégalie, from acro- + Greek megal-, stem of megas big
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for acromegaly

"gigantism due to activity of pituitary after normal growth has ceased," 1886, from French acromégalie, from medical Latin acromegalia, from Greek akron "extremity" (see acrid) + megas "great" (fem. megale; see mickle). Said in contemporary literature to have been coined 1885 by French physician Dr. Pierre Marie.

Online Etymology Dictionary, © 2010 Douglas Harper
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acromegaly in Medicine

acromegaly ac·ro·meg·a·ly (āk'rō-měg'ə-lē)
A disorder marked by progressive enlargement of the head, face, hands, feet, and chest due to excessive secretion of growth hormone by the anterior lobe of the pituitary gland. Also called Marie's disease.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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