allosteric

American  

[al-uh-ster-ik, -steer-] / ˌæl əˈstɛr ɪk, -ˈstɪər- /

adjective

Biochemistry.

1. pertaining to regulation of the rate of an enzymatic process.

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allosteric British  

/ ˌæləʊˈstɪərɪk /

adjective

1. biochem of, relating to, or designating a function of an enzyme in which the structure and activity of the enzyme are modified by the binding of a metabolic molecule

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Other Word Forms

Derived Forms

• allosterically
  adverb

Etymology

Origin of allosteric

First recorded in 1960–65; allo- + steric

Example Sentences

"It provided new insights into the allosteric network linking the ligand binding pocket to the G protein binding site that governs efficacy and potency."

From Science Daily • Dec. 21, 2023

Drugs that target allosteric sites are generally safer and more effective compared to drugs targeting active sites.

From Science Daily • Dec. 18, 2023

The authors of the study mapped the allosteric sites by using a technique called deep mutational scanning.

From Science Daily • Dec. 18, 2023

What other molecules in the cell provide enzymatic regulation such as allosteric modulation, and competitive and non-competitive inhibition?

From Textbooks • Apr. 25, 2013

When an allosteric inhibitor binds to a region on an enzyme, all active sites on the protein subunits are changed slightly such that they bind their substrates with less efficiency.

From Textbooks • Apr. 25, 2013