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angiostatin

American  
[an-jee-oh-stat-n] / ˌæn dʒi oʊˈstæt n /

noun

Biochemistry.
  1. a naturally occurring protein that inhibits endothelial proliferation and interferes with the growth of new blood vessels, investigated for use as an anticancer drug.


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Another antiangiogenesis compound, angiostatin, discovered by Folkman's colleague Dr. Michael O'Reilly, makes colon, breast and prostate tumors shrink in mice.

From Time Magazine Archive

The rodents were given angiostatin for more than 50 days, the equivalent of five years for humans, and their tumors stayed small as long as they took the drug.

From Time Magazine Archive

So what if angiostatin and endostatin work only in mice?

From Time Magazine Archive

Within a year or two, EntreMed and its partner in the project, Bristol-Myers-Squibb, will probably figure out how to make angiostatin in quantity.

From Time Magazine Archive

At this stage all EntreMed can offer is some very interesting molecules, called angiostatin and endostatin, and the only cancers they have cured so far have been in mice.

From Time Magazine Archive

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