- either of two genes (BRCA1 or BRCA2) that, if inherited in a mutated form, may predispose some carriers to develop breast or ovarian cancer.
Origin of BRCA
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
Examples from the Web for brca1
The case centers around Myriad, which has patents on BRCA1 and BRCA2, genes that are linked to a very high risk of breast cancer.It’s in the Genes
June 13, 2013
- A tumor suppressor gene that, when inherited in a mutated state, is associated with the development of various cancers, especially breast and ovarian cancer.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
- One of two genes (designated BRCA1 and BRCA2) that help repair damage to DNA, but when inherited in a defective state increase the risk of breast and ovarian cancer.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.