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either of two genes (BRCA1 or BRCA2) that, if inherited in a mutated form, may predispose some carriers to develop breast or ovarian cancer.
Origin of BRCA
1900-95; initialism from br(east) and ca(ncer) Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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Examples from the Web for brca1
Contemporary Examples
  • The case centers around Myriad, which has patents on brca1 and BRCA2, genes that are linked to a very high risk of breast cancer.

brca1 in Medicine

BRCA1 (bē'är-sē'ā-wŭn')
A defective gene associated with the development of familial breast cancer.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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brca1 in Science
One of two genes (designated BRCA1 and BRCA2) that help repair damage to DNA, but when inherited in a defective state increase the risk of breast and ovarian cancer.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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