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[sen-truh-meer] /ˈsɛn trəˌmɪər/
noun, Cell Biology.
a specialized structure on the chromosome, appearing during cell division as the constricted central region where the two chromatids are held together and form an X shape.
Origin of centromere
First recorded in 1920-25; centro- + -mere
Related forms
[sen-truh-mer-ik, -meer-] /ˌsɛn trəˈmɛr ɪk, -ˈmɪər-/ (Show IPA),
adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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British Dictionary definitions for centromere


the dense nonstaining region of a chromosome that attaches it to the spindle during mitosis
Derived Forms
centromeric (ˌsɛntrəˈmɛrɪk; -ˈmɪərɪk) adjective
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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centromere in Medicine

centromere cen·tro·mere (sěn'trə-mēr')
The most condensed and constricted region of a chromosome to which the spindle fiber is attached during mitosis. Also called kinetochore.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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centromere in Science
The region of the chromosome to which the spindle fiber is attached during cell division (both mitosis and meiosis). The centromere is the constricted point at which the two chromatids forming the chromosome are joined together. See more at meiosis, mitosis.

The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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