Try Our Apps


Avoid these words. Seriously.


[koh-fak-ter] /ˈkoʊˌfæk tər/
Biochemistry. any of various organic or inorganic substances necessary to the function of an enzyme.
  1. a prefactor or postfactor.
  2. the product of the minor of a given element of a matrix times −1 raised to the power of the sum of the indices of the row and column crossed out in forming the minor.
Origin of cofactor
First recorded in 1935-40; co- + factor Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
Cite This Source
British Dictionary definitions for cofactor


(maths) a number associated with an element in a square matrix, equal to the determinant of the matrix formed by removing the row and column in which the element appears from the given determinant See minor
(biochem) a nonprotein substance that forms a complex with certain enzymes and is essential for their activity. It may be a metal ion or a coenzyme
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
Cite This Source
cofactor in Medicine

cofactor co·fac·tor (kō'fāk'tər)
A substance, such as a metallic iron or coenzyme, that must be associated with an enzyme for the substance to function.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
Cite This Source
cofactor in Science
A substance, such as a metallic ion or a coenzyme, that must be associated with an enzyme for the enzyme to function. Cofactors work by changing the shape of an enzyme or by actually participating in the enzymatic reaction.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
Cite This Source

Word of the Day

Nearby words for cofactor

Word Value for cofactor

Scrabble Words With Friends