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[kree-at-n-een, -in] /kriˈæt nˌin, -ɪn/
noun, Biochemistry.
a crystalline end product of creatine metabolism, C 4 H 7 N 3 O, occurring in urine, muscle, and blood.
Origin of creatinine
1850-55; < German Kreatinin, equivalent to kreatin creatine + -in -ine2 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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Examples from the Web for creatinine
Historical Examples
  • The creatinine was estimated in two cases and was found to be 2.0 mg.

    Scurvy Past and Present Alfred Fabian Hess
  • Foremost among them are uric acid, creatinine, and the coloring-matter.

  • The precipitate contains the picrate of trimethylenediamine, mixed with the picrates of cadaverine and creatinine.

    Poisons: Their Effects and Detection Alexander Wynter Blyth
  • Creatine and creatinine also seem to lessen in amount, but of the extent of this change I am not as yet fully informed.

    Fat and Blood S. Weir Mitchell
British Dictionary definitions for creatinine


an anhydride of creatine that is abundant in muscle and excreted in the urine
Word Origin
C19: from German Kreatinin, from Kreatincreatine + -in-ine²
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for creatinine

by 1847, from creatine + chemical suffix -ine (2).

Online Etymology Dictionary, © 2010 Douglas Harper
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creatinine in Medicine

creatinine cre·at·i·nine (krē-āt'n-ēn', -ĭn)
A creatine anhydride formed by the metabolism of creatine and found in muscle tissue and blood and normally excreted in the urine as metabolic waste.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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creatinine in Science
  (krē-āt'n-ēn', -ĭn)   
A compound formed by the metabolism of creatine, found in muscle tissue and blood and normally excreted in the urine as a metabolic waste. Measurement of creatinine levels in the blood is used to evaluate kidney function. Chemical formula: C4H7N3O.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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