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Cushing's disease

noun, Pathology.
a disease characterized by abnormal accumulations of facial and trunk fat, fatigue, hypertension, and osteoporosis, caused by hyperfunction of the adrenal cortex or administration of adrenal cortical hormones.
Also called Cushing's syndrome.
Origin of Cushing's disease
1935-40; after H. W. Cushing, who first described it Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2017.
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British Dictionary definitions for cushing's syndrome

Cushing's disease

a rare condition caused by excess corticosteroid hormones in the body, characterized chiefly by obesity of the trunk and face, high blood pressure, fatigue, and loss of calcium from the bones
Word Origin
C20: named after Harvey Williams Cushing (1869–1939), US neurosurgeon
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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cushing's syndrome in Medicine

Cushing's syndrome Cush·ing's syndrome (kush'ĭngz)
A syndrome caused by an increased production of ACTH from a tumor of the adrenal cortex or of the anterior lobe of the pituitary gland. It is characterized by obesity and weakening of the muscles. Also called Cushing's basophilism, pituitary basophilism.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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cushing's syndrome in Science
Cushing's syndrome
A syndrome caused by an excess of corticosteroids, especially cortisol, in the blood, characterized by obesity, muscle and skin atrophy, facial fullness (known as moon facies), hypertension, and other physical changes. Glucocorticoid excess is usually caused by a tumor of the adrenal cortex, excessive intake of ACTH or glucocorticoids, or increased production of ACTH from a tumor of the anterior lobe of the pituitary gland. Cushing's syndrome is named after its discoverer, American neurosurgeon Harvey Williams Cushing (1869-1939).
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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