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disease

American  
[dih-zeez] / dɪˈziz /

noun

  • diseases
    plural
  1. An image of the word disease as defined by a disordered or incorrectly functioning organ, part, structure, or system of the body resulting from the effect of genetic or developmental errors, infection, poisons, nutritional deficiency or imbalance, toxicity, or unfavorable environmental factors; illness; sickness; ailment.

    a disordered or incorrectly functioning organ, part, structure, or system of the body resulting from the effect of genetic or developmental errors, infection, poisons, nutritional deficiency or imbalance, toxicity, or unfavorable environmental factors; illness; sickness; ailment.

    Synonyms:
    malady, disorder, infirmity, indisposition, distemper, derangement, complaint, morbidity
    Antonyms:
    health
  2. any abnormal condition in a plant that interferes with its vital physiological processes, caused by pathogenic microorganisms, parasites, unfavorable environmental, genetic, or nutritional factors, etc.

  3. any harmful, depraved, or morbid condition, as of the mind or society.

    His fascination with executions is a disease.

  4. decomposition of a material under special circumstances.

    tin disease.


verb (used with object)

diseased, diseasing
  1. to affect with disease; make ill.

    Antonyms:
    cure
disease British  
/ dɪˈziːz /

noun

  1. any impairment of normal physiological function affecting all or part of an organism, esp a specific pathological change caused by infection, stress, etc, producing characteristic symptoms; illness or sickness in general

  2. a corresponding condition in plants

  3. any situation or condition likened to this

    the disease of materialism

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Derived Forms

Inflected Forms

Nouns


Etymology

Origin of disease

First recorded in 1300–50; Middle English disese, from Anglo-French dese(a)se, disaise; dis- 1 + ease


Explanation

A disease is a health condition that has a specific set of symptoms and traits — such as malaria or heart disease. Disease is not always about the human body being sick. Plants and animals are often the victims of disease. People also use the word disease in a more figurative sense to illustrate just how bad or damaging a negative influence can be — like the disease of greed among capitalists or the disease of plagiarism among college students.

Keep Reading on Vocabulary.com

Vocabulary lists containing disease

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

He said intelligence is the ability to solve problems creatively, such as winning at chess, driving a car and curing a disease.

From Los Angeles Times ● Nov. 2, 2026

People with prolonged residential exposure to chlorpyrifos had more than 2.5 times the risk of Parkinson's disease compared with those who had no such exposure.

From Science Daily ● Nov. 1, 2026

These conditions included cardiovascular disease, which affects the heart and blood vessels, and cerebrovascular disease, which involves blood vessels that supply the brain.

From Science Daily ● Nov. 1, 2026

Although inherited genetic factors can influence who develops Parkinson's, researchers have increasingly focused on environmental exposures that may also contribute to the disease.

From Science Daily ● Nov. 1, 2026

His family wiped out by disease and war, fourteen-year-old orphan Andrew Jackson first lived with relatives and later moved to North Carolina.

From "In the Shadow of Liberty" by Kenneth C. Davis

Radiologists are doctors who specialise in using images to diagnose and manage medical conditions and diseases.

From BBC ● Nov. 1, 2026

And it seems that these undetected flares may contribute to several of the hallmark diseases of old age.

From Slate ● Nov. 1, 2026

Soriot said in the results statement that the group continues "to invest in AI technology to tackle complex diseases".

From Barron's ● Oct. 30, 2026

“Essentially the only way to really diagnose these conditions together is after an autopsy and to see the hallmark features of the diseases under the microscope,” Vossel said.

From Los Angeles Times ● Oct. 30, 2026

And the more we got sick, the more diseases spread.

From "Lost Boy, Lost Girl" by John Bul Dau

"Boosting immune cell fitness may also help with other conditions where the immune system fails to clear diseased cells," Beyaz says.

From Science Daily ● Oct. 16, 2026

A new class of medications—known as “protein degraders”—are showing promise in going after a certain kind of hard-to-target protein in diseased cells.

From The Wall Street Journal ● Oct. 15, 2026

The first starts with terror of the unknown and unseen but culminates in sheer pathos; the latter keeps the reader guessing: Is the creature real or merely the product of a diseased imagination?

From The Wall Street Journal ● Oct. 9, 2026

He is also concerned about unregulated nurseries selling unidentified, or diseased plants.

From BBC ● Sep. 4, 2026

Instead, we began going to another site at the other end of the veld, where a chicken factory, Sunnyside, dumped loads of dead, diseased chickens, and rejected eggs.

From "Kaffir Boy: An Autobiography" by Mark Mathabane

In either case we have diabetes, the sugar irritating and diseasing the kidneys as it passes.”

From Alcohol: A Dangerous and Unnecessary Medicine, How and Why What Medical Writers Say by Martha Meir Allen

They provide for your wants, hearken to your complaints, nurture you in sickness, with a diseasing fondness, and so render you incapable.

From Charlemont; Or, the Pride of the Village. a Tale of Kentucky by William Gilmore Simms

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