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disease

American  
[dih-zeez] / dɪˈziz /

noun

  • diseases
    plural
  1. a disordered or incorrectly functioning organ, part, structure, or system of the body resulting from the effect of genetic or developmental errors, infection, poisons, nutritional deficiency or imbalance, toxicity, or unfavorable environmental factors; illness; sickness; ailment.

    Synonyms:
    malady, disorder, infirmity, indisposition, distemper, derangement, complaint, morbidity
    Antonyms:
    health
  2. any abnormal condition in a plant that interferes with its vital physiological processes, caused by pathogenic microorganisms, parasites, unfavorable environmental, genetic, or nutritional factors, etc.

  3. any harmful, depraved, or morbid condition, as of the mind or society.

    His fascination with executions is a disease.

  4. decomposition of a material under special circumstances.

    tin disease.


verb (used with object)

diseased, diseasing
  1. to affect with disease; make ill.

    Antonyms:
    cure
disease British  
/ dɪˈziːz /

noun

  1. any impairment of normal physiological function affecting all or part of an organism, esp a specific pathological change caused by infection, stress, etc, producing characteristic symptoms; illness or sickness in general

  2. a corresponding condition in plants

  3. any situation or condition likened to this

    the disease of materialism

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Derived Forms

Inflected Forms

Nouns

Etymology

Origin of disease

First recorded in 1300–50; Middle English disese, from Anglo-French dese(a)se, disaise; dis- 1 + ease

Explanation

A disease is a health condition that has a specific set of symptoms and traits — such as malaria or heart disease. Disease is not always about the human body being sick. Plants and animals are often the victims of disease. People also use the word disease in a more figurative sense to illustrate just how bad or damaging a negative influence can be — like the disease of greed among capitalists or the disease of plagiarism among college students.

Keep Reading on Vocabulary.com

Vocabulary lists containing disease

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

After Walker’s death, a medical examiner ruled that she died of hypertensive cardiovascular disease with preeclampsia, the latter of which is a dangerous pregnancy-related high blood pressure condition that doctors had identified in Walker.

From Salon Sep. 17, 2026

"It's a disease of a significant unmet medical need," says Brian Cunniff, a professor at the University of Vermont.

From Science Daily Sep. 17, 2026

The latest government figures show there have been more than 194,000 cases since March from the highly contagious disease, which spreads easily through breathing, coughing or sneezing.

From BBC Sep. 17, 2026

The earlier results suggested that a high dose of the therapy slowed disease progression by 75% compared with a historical database of patients.

From The Wall Street Journal Sep. 16, 2026

His family wiped out by disease and war, fourteen-year-old orphan Andrew Jackson first lived with relatives and later moved to North Carolina.

From "In the Shadow of Liberty" by Kenneth C. Davis

This persistent inflammation has been associated with numerous diseases that become more common later in life.

From Science Daily Sep. 14, 2026

The Food and Drug Administration has adopted these modern methods to approve new drugs for other slow-progressing diseases, including Alzheimer’s, osteoporosis and metabolic liver disease.

From The Wall Street Journal Sep. 13, 2026

But that wasn’t the case, and those exposed are now at elevated risks of cardiovascular and respiratory diseases, not to mention cancer.

From Salon Sep. 12, 2026

This year, a seventh bell was rung to commemorate the thousands who died from diseases including cancer after the attacks.

From BBC Sep. 11, 2026

Neither did the early farmers understand that feeding children with more porridge and less breast milk would weaken their immune system, and that permanent settlements would be hotbeds for infectious diseases.

From "Sapiens: A Brief History of Humankind" by Yuval Noah Harari

He is also concerned about unregulated nurseries selling unidentified, or diseased plants.

From BBC Sep. 4, 2026

Those changes were even more pronounced in diseased livers.

From Science Daily Sep. 3, 2026

Cells in the diseased livers had started moving away from their mature state and toward the regenerative state, but they were unable to finish the transition.

From Science Daily Aug. 31, 2026

In particular, they’re examining how bacteria from diseased gums, and the immune response they trigger, may contribute to conditions including heart disease, diabetes, cognitive decline, arthritis, respiratory disease and chronic liver disease.

From The Wall Street Journal Jul. 26, 2026

A television journalist in the Farm Belt once said this about a suspected outbreak of hoof-and-mouth disease: The pasture contained several cows seen by news reporters that were dead, diseased, or dying.

From "Woe Is I" by Patricia T. O'Conner

In either case we have diabetes, the sugar irritating and diseasing the kidneys as it passes.”

From Alcohol: A Dangerous and Unnecessary Medicine, How and Why What Medical Writers Say by Martha Meir Allen

They provide for your wants, hearken to your complaints, nurture you in sickness, with a diseasing fondness, and so render you incapable.

From Charlemont; Or, the Pride of the Village. a Tale of Kentucky by William Gilmore Simms

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