drug
1 Americannoun
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Pharmacology. a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well-being.
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(in federal law)
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any substance recognized in the official pharmacopoeia or formulary of the nation.
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any substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in humans or other animals.
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any article, other than food, intended to affect the structure or any function of the body of humans or other animals.
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any substance intended for use as a component of such a drug, but not a device or a part of a device.
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a habit-forming medicinal or illicit substance, especially a narcotic.
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drugs,
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chemical substances prepared and sold as pharmaceutical items, either by prescription or over the counter.
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personal hygienic items sold in a drugstore, as toothpaste, mouthwash, etc.
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Obsolete. any ingredient used in chemistry, pharmacy, dyeing, or the like.
verb (used with object)
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to administer a medicinal drug to.
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to stupefy or poison with a drug.
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to mix (food or drink) with a drug, especially a stupefying, narcotic, or poisonous drug.
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to administer anything nauseous to.
verb phrase
idioms
verb
noun
noun
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any synthetic, semisynthetic, or natural chemical substance used in the treatment, prevention, or diagnosis of disease, or for other medical reasons
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a chemical substance, esp a narcotic, taken for the pleasant effects it produces
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a commodity available in excess of the demands of the market
verb
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to mix a drug with (food, drink, etc)
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to administer a drug to
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to stupefy or poison with or as if with a drug
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A chemical substance, especially one prescribed by a medical provider, that is used in the diagnosis, treatment, or prevention of a condition or disease. Drugs are prescribed for a limited amount of time, as for an acute infection, or on a regular basis for chronic disorders, such as hypertension.
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A chemical substance such as a narcotic or a hallucinogen that affects the central nervous system and is used recreationally for perceived desirable effects on personality, perception, or behavior. Many recreational drugs are used illicitly and can be addictive.
Other Word Forms
Derived Forms
Etymology
Origin of drug1
First recorded in 1300–50; Middle English drogges (plural), from Middle French drogue, of obscure origin
Origin of Drug3
From the Avestan word drauga
Explanation
A drug is a medicine. Before you travel to India, your doctor may prescribe a drug to protect you from getting malaria. A substance that makes a change in your body is a drug. Most often, a drug is medicine prescribed by a doctor to protect a patient from illness, cure them, or relieve their pain. Drug also means an illegal substance taken simply for the way it makes the user feel. Drug is also a verb that describes both taking illegal drugs and giving someone a drug secretly, such as slipping it into their food or drink.
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Nestlé divested Aimmune’s signature drug Palforzia in September 2023, about three years after buying the company for $2.6 billion.
From Barron's • Jun. 10, 2026
The company reported positive results for two studies of its elecoglipron experimental drug, which showed competitive efficacy with a standard safety profile, the analysts say.
From The Wall Street Journal • Jun. 9, 2026
Her doctors say there is another drug trial option in case it is not successful - but she has been advised that these treatments are not curative.
From BBC • Jun. 9, 2026
The acquisition, GSK’s largest in eight years, aims to bolster its cancer drug pipeline with Nuvalent’s two experimental lung-cancer drugs.
From Barron's • Jun. 9, 2026
After my mother was arrested in the sweatshop immigration raid, a prison doctor had given her a shot of a drug to keep her calm overnight; That shot, my mother believed, caused Caroline’s condition.
From "Krik? Krak!" by Edwidge Danticat
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.