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[ih-pis-tuh-sis] /ɪˈpɪs tə sɪs/
noun, plural epistases
[ih-pis-tuh-seez] /ɪˈpɪs təˌsiz/ (Show IPA)
Genetics. a form of interaction between nonallelic genes in which one combination of such genes has a dominant effect over other combinations.
  1. the stoppage of a secretion or discharge.
  2. a scum that forms on a urine specimen upon standing.
Origin of epistasis
First recorded in 1915-20, epistasis is from the Greek word epístasis stopping, stoppage. See epi-, stasis
Related forms
[ep-uh-stat-ik] /ˌɛp əˈstæt ɪk/ (Show IPA),
adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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British Dictionary definitions for epistasis


(obsolete) scum on the surface of a liquid, esp on an old specimen of urine
(med) the arrest or checking of a bodily discharge, esp bleeding
(genetics) Also called hypostasis. the suppression by a gene of the effect of another gene that is not its allele
Derived Forms
epistatic (ˌɛpɪˈstætɪk) adjective
Word Origin
C19: from Greek: a stopping, from ephistanai to stop, from epi- + histanai to put
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for epistasis

medical Latin, from Greek epistasis "a stopping, stoppage," from epi "upon" (see epi-) + stasis "a stopping or standing" (see stasis).

Online Etymology Dictionary, © 2010 Douglas Harper
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epistasis in Medicine

epistasis e·pis·ta·sis (ĭ-pĭs'tə-sĭs)
n. pl. e·pis·ta·ses (-sēz')

  1. A film that forms over the surface of a urine specimen.

  2. An interaction between nonallelic genes, especially an interaction in which one gene suppresses the expression of another.

  3. The suppression of a bodily discharge or secretion.

ep'i·stat'ic (ěp'ĭ-stāt'ĭk) adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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