fibrinogen

American  

[fahy-brin-uh-juhn] / faɪˈbrɪn ə dʒən /

noun

Biochemistry.

1. a globulin occurring in blood and yielding fibrin in blood coagulation.

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fibrinogen British  

/ fɪˈbrɪnədʒən /

noun

1. a soluble protein, a globulin, in blood plasma, converted to fibrin by the action of the enzyme thrombin when blood clots

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fibrinogen Scientific  

/ fī-brĭn′ə-jən /

1. A protein in the blood plasma that is essential for the coagulation of blood. It is converted to fibrin by the action of thrombin in the presence of calcium ions.

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Other Word Forms

• fibrinogenic
  adjective

Etymology

Origin of fibrinogen

First recorded in 1870–75; fibrino- + -gen

Compare meaning

How does fibrinogen compare to similar and commonly confused words? Explore the most common comparisons:

• fibrin vs. fibrinogen

Example Sentences

See Examples For:

fibrinogen

A humanized antibody that blocks the inflammatory region of fibrinogen is currently in phase-1 trials after animal studies showed protection against neuronal loss.

From Science Daily ● Jan. 8, 2026

Earlier work from the group showed that Aβ binds to fibrinogen and connected that interaction to the progression of Alzheimer's disease.

From Science Daily ● Oct. 22, 2025

Chitosan is already used in some hemostats: its positively charged surface is known to strongly attract negatively charged platelets and fibrinogen, the two major components of a blood clot.

From Science Daily ● Jan. 22, 2024

The second protein, fibrinogen, is produced in the liver and causes clotting to stop bleeding.

From Scientific American ● Sep. 1, 2023

The last step in the change is the action of thrombin upon fibrinogen to form fibrin, and the clot is complete.

From Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea" by Various