To confront; face; challenge: So that's the kind of piffle actors have to go up against (1940s+)
Nobody wanted to go up against that inner circle, and few in the government dared.
We need to be smart here to get a pro-family conservative to go up against Mitt Romney.
They had hoped to win, but it was a big thing to go up against a six cylindered craft with a four.
Man is the hardest proposition a woman has to go up against.
It'll all work out right before we go up against Herne in June.
"I'm not fool enough to go up against that war-club," he remarked.
Never could they go up against the tide if he did not pull more strongly.
I fancy he means to go up against this fresh duck Merriwell and do him.
When I go up against a thing like that on the sections, I fire the whole bunch and import a few more Italians.
You can go up against the ugliness of life and never—not for an instant—even realize what you touch.