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goldstein's toe sign in Medicine

Goldstein's toe sign

(gōldstīnz)
n.
  1. Increased space between the big toe and its neighbor, seen in Down syndrome and, occasionally, cretinism.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.