achondroplasia

American  

[ay-kon-druh-play-zhuh, -zhee-uh, -zee-uh] / eɪˌkɒn drəˈpleɪ ʒə, -ʒi ə, -zi ə /

noun

Pathology.

1. defective conversion of cartilage into bone, especially at the epiphyses of long bones, producing a type of dwarfism.

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achondroplasia British  

/ eɪˌkɒndrəʊˈpleɪzɪə /

noun

1. a skeletal disorder, characterized by failure of normal conversion of cartilage into bone, that begins during fetal life and results in dwarfism

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Other Word Forms

• achondroplastic
  adjective

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Etymology

Origin of achondroplasia

First recorded in 1890–95; a- ⁶ + chondro- + -plasia

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Example Sentences

See Examples For:

achondroplasia

The reboot was criticised by Game of Thrones actor Peter Dinklage, who has a form of dwarfism called achondroplasia, for being "backward".

From BBC ● Mar. 16, 2025

Dinklage, who has a form of dwarfism called achondroplasia, criticised the film in 2022 during an interview with podcaster Marc Maron.

From BBC ● Mar. 13, 2025

Professor Savarirayan said the team had started a phase III trial and planning was underway into further studies into children aged 0-3 years with achondroplasia.

From Science Daily ● Nov. 18, 2024

The study, sponsored by BridgeBio Pharma Inc, involved 72 children with achondroplasia from Australia, the UK, the US, Spain, France and Canada.

From Science Daily ● Nov. 18, 2024

Analogous to rachitis is achondroplasia, or the so called fetal rickets—a disease in which deformity results from an arrest, absence, or perversion of the normal process of enchondral ossification.

From Anomalies and Curiosities of Medicine by Walter L. (Walter Lytle) Pyle

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