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hypogonadism

American  
[hahy-puh-goh-na-diz-uhm, -gon-a-] / ˌhaɪ pəˈgoʊ næˌdɪz əm, -ˈgɒn æ- /
Also hypogonadia

noun

Pathology.
  1. diminished hormonal or reproductive functioning in the testes or the ovaries.

  2. a manifestation of this, as delayed pubescence or Klinefelter's syndrome.


Etymology

Origin of hypogonadism

First recorded in 1915–20; hypo- + gonad + -ism


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

But according to the endocrinologist Dr. Marcus Goncalves, it doesn’t make sense for men to hack their testosterone unless they’re in the minority who suffer from hypogonadism, meaning the body produces very little testosterone.

From The Wall Street Journal ● Sep. 12, 2026

Previous research had revealed that mutations in genes associated with TACR3 led to a condition known as "congenital hypogonadism," resulting in reduced sex hormone production, including testosterone.

From Science Daily ● Jan. 22, 2024

But the trial’s results provide important information for physicians and patients who have hypogonadism, because many physicians, and patients, may have been reluctant to treat the condition because of concerns about heart disease.

From New York Times ● Jun. 16, 2023

Testosterone was isolated and synthesized in 1935 and first used to treat hypogonadism in men as well as tumor growth in women.

From Salon ● Dec. 6, 2022

Unless someone has hypogonadism brought on by chemotherapy, infection or another serious medical condition, the FDA discourages its use.

From Seattle Times ● Jun. 29, 2022

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