Yes, Will Gardner is irreplaceable, and will forever be missed.
I lost contact with friends and acquaintances, irreplaceable photos from mobile uploads, and my faith in social media.
“The life and work of Barnaby Jack are legendary and irreplaceable,” it said.
Killing these iconic birds is not just an irreplaceable loss for a vulnerable species.
Whether or not Garafolo is irreplaceable in that effort is another matter.
In that case you shall have consumed ten pounds of irreplaceable metal.
Five irreplaceable generals were dead; six more, wounded or captured.
And from this it follows that each man is not only unique, but irreplaceable.
We need not regard them conceptually as unchangeable or irreplaceable.
The truth of the matter is that everything that is original is irreplaceable.
1807, from assimilated form of in- (1) "not, opposite of" + replaceable. Related: Irreplaceably.