If Palin runs, wins the nomination and then loses the general election, she could leave the Republican brand in pieces.
If Romney loses Ohio and its 18 electoral votes, it is very difficult to win the White House.
In addition, once Murdoch buys a property, he almost never lets it go, no matter how much money it loses.
When the “moderate” option for Western fighters in Syria is Al Qaeda, the term “moderate” loses all meaning.
The White House gets nothing from an increase in the debt ceiling, just as the GOP loses nothing from raising it.
Then, when that plot completely fails, Sanballat loses his temper.
Lady Hunter little supposes what she loses in not cultivating them.
After three or four runs of luck, he loses and leaves the table, according to the instructions conveyed by his confederate.
How many shots is a fellow to have before he loses his chance?
Religious faith is a positive achievement, and he who does not deliberately choose it, loses it.
Old English losian "be lost, perish," from los "destruction, loss," from Proto-Germanic *lausa- (cf. Old Norse los "the breaking up of an army;" Old English forleosan "to lose, destroy," Old Frisian forliasa, Old Saxon farliosan, Middle Dutch verliesen, Old High German firliosan, German verlieren), from PIE root *leu- "to loosen, divide, cut apart, untie, separate" (cf. Sanskrit lunati "cuts, cuts off," lavitram "sickle;" Greek lyein "to loosen, untie, slacken," lysus "a loosening;" Latin luere "to loose, release, atone for, expiate").
Replaced related leosan (a class II strong verb whose past participle loren survives in forlorn and lovelorn), from Proto-Germanic *leusanan (cf. Old High German virliosan, German verlieren, Old Frisian urliasa, Gothic fraliusan "to lose").
Transitive sense of "to part with accidentally" is from c.1200. Meaning "fail to maintain" is from mid-15c. Meaning "to be defeated" (in a game, etc.) is from 1530s. Meaning "to cause (someone) to lose his way" is from 1640s. To lose (one's) mind "become insane" is attested from c.1500. To lose out "fail" is 1858, American English. Related: Lost; losing.