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a combining form with the meanings “large, great, grand,” “abnormally large,” used in the formation of compound words:
megalopolis; megalocardia.
Also, especially before a vowel, megal-.
Compare mega-.
Origin of megalo-
< Greek, combining form of megal- (stem of mégas) great, large Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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British Dictionary definitions for megalo-


combining form
indicating greatness, or abnormal size: megalopolis, megaloblast
Word Origin
from Greek megas great
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for megalo-

word-forming element meaning "large, great, exaggerated," from comb. form of Greek megas "large, great" (stem megal-); see mickle.

Online Etymology Dictionary, © 2010 Douglas Harper
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megalo- in Medicine

megalo- or megal-
Large; of exaggerated size or greatness: megalocephaly.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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