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[meg-uh-luh-blast] /ˈmɛg ə ləˌblæst/
noun, Pathology.
an abnormally large, immature, and dysfunctional red blood cell found in the blood of persons with pernicious anemia or certain other disorders.
Origin of megaloblast
First recorded in 1895-1900; megalo- + -blast
Related forms
megaloblastic, adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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Examples from the Web for megaloblastic
Historical Examples
  • We can now say that the megaloblastic metamorphosis is not a purposeful process, and for the following reasons: 1.

    Histology of the Blood Paul Ehrlich
  • Since the fresh formation of red blood corpuscles by means of the megaloblastic method is clearly much slower.

    Histology of the Blood Paul Ehrlich
  • For this reason, the prognosis of megaloblastic anæmia, apart from the group of Bothriocephalus anæmia, is exceedingly bad.

    Histology of the Blood Paul Ehrlich
  • In agreement with this, "blood crises" are not to be observed in the megaloblastic anæmias.

    Histology of the Blood Paul Ehrlich
British Dictionary definitions for megaloblastic


an abnormally large red blood cell precursor, present in certain types of anaemia
Derived Forms
megaloblastic (ˌmɛɡələʊˈblæstɪk) adjective
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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megaloblastic in Medicine

megaloblast meg·a·lo·blast (měg'ə-lō-blāst')
An abnormally large nucleated red blood cell found especially in pernicious anemia or in certain vitamin deficiencies.

meg'a·lo·blas'tic adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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