Acacius, bishop of Melitene, endeavoured to convert Nestorius.
Melitene was also the name of the district in which this town was situated.
He also captured the castles of the mountaineers of Melitene.
Accordingly Valesius concludes that Melitene was not the name of the legion, but of the town in which it was stationed.
Another important road connected Sision with Cocysus and Melitene.