- Pathology. (of malignant cells or disease-producing organisms) to spread to other parts of the body by way of the blood or lymphatic vessels or membranous surfaces.
- to spread injuriously: Street gangs have metastasized in our city.
- to transform, especially into a dangerous form: The KGB metastasized after the fall of the Soviet Union. Truth metastasized into lurid fantasy.
Also especially British, me·tas·ta·sise.
Origin of metastasize
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- pathol (esp of cancer cells) to spread to a new site in the body via blood or lymph vessels
- (of a problem) to deteriorate or spread into new areas
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
Word Origin and History for metastasise
chiefly British English spelling of metastasize. Related: Metastasised; metastasising.
Online Etymology Dictionary, © 2010 Douglas Harper
- To be transmitted or transferred by or as if by metastasis.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.