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[mon-uh-vey-luh nt] /ˌmɒn əˈveɪ lənt/
Chemistry. univalent.
  1. containing only one kind of antibody.
  2. pertaining to an antibody fragment with one antigen-binding site.
Origin of monovalent
First recorded in 1865-70; mono- + -valent
Related forms
monovalence, monovalency, noun Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2017.
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Examples from the Web for monovalent
Contemporary Examples
Historical Examples
  • For the sake of simplicity we can assume that these ions are all monovalent.

    Animal Proteins Hugh Garner Bennett
  • Cholesterine, ko-les′te-rin, n. a substance occurring abundantly in bile and biliary calculi, probably a monovalent alcohol.

  • monovalent atoms are those which can, under no circumstances, unite with more than one other atom.

    The Making of Species Douglas Dewar
  • Similarly, a trivalent atom, such as that of Nitrogen, can unite with three monovalent atoms.

    The Making of Species Douglas Dewar
  • A tetravalent atom, such as that of Carbon, can combine with four monovalent atoms.

    The Making of Species Douglas Dewar
British Dictionary definitions for monovalent


  1. having a valency of one
  2. having only one valency
Also univalent
Derived Forms
monovalence, monovalency, noun
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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monovalent in Medicine

monovalent mon·o·va·lent (mŏn'ə-vā'lənt)

  1. Able to form only one covalent or ionic bond.

  2. Having a valence of one; univalent.

  3. Of or relating to an antiserum containing an antibody or antibodies specific for one antigen.

  4. Containing antigens from a single strain of a microorganism.

  5. Having only one site of attachment. Used of an antibody or antigen.

mon'o·va'lence or mon'o·va'len·cy n.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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monovalent in Science
  1. Having a valence of 1; univalent.

  2. Containing antibodies with specific activity against a single strain of a microorganism or against antigens from such a strain.

The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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