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macrocephaly

British  
/ ˌmækrəʊˈsɛfəlɪ, ˌmækrəʊsɪˈfeɪlɪə, ˌmækrəʊsɪˈfælɪk /

noun

  1. the condition of having an abnormally large head or skull

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

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Scientists suspect that a mutated Pten gene is one of the contributing factors to autism and have shown its association with macrocephaly, the abnormal development of an enlarged brain and head.

From Science Daily • Dec. 13, 2023

For instance, duplications within the chromosomal region 1q21 are associated with autism and macrocephaly, while deletions are linked to schizophrenia and microcephaly.

From Salon • Jun. 9, 2018

Augmentation of the volume of the head is called macrocephaly, and there are a number of curious examples related.

From Anomalies and Curiosities of Medicine by Pyle, Walter L. (Walter Lytle)

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