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neural tube defect

noun, Pathology.
any of a group of congenital abnormalities involving the brain and spinal cord, including spina bifida and meningocele, caused by failure of the neural tube to close properly during embryonic development.
Origin of neural tube defect
First recorded in 1885-90 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2017.
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