nicotinamide

[nik-uh-tin-uh-mahyd, -mid, -tee-nuh-]

noun

Biochemistry.

1. a colorless, crystalline, water-soluble solid, C 6 H 6 N 2 O, the amide of nicotinic acid, and a component of the vitamin-B complex, found in meat, liver, fish, whole wheat, and eggs: used in medicine chiefly as an agent for preventing or treating human pellagra or animal black tongue.

nicotinamide

/ ˌnɪkəˈtɪnəˌmaɪd, -ˈtiːn- /

noun

1. the amide of nicotinic acid: a component of the vitamin B complex and essential in the diet for the prevention of pellagra. Formula: C 6 H 6 ON 2

Word History and Origins

Origin of nicotinamide¹

First recorded in 1890–95; nicotine + amide

Example Sentences

Since 2015, dermatologists have advised many patients with a history of skin cancer to consider taking nicotinamide, a form of vitamin B3.

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That recommendation was based on a clinical trial involving 386 participants, which found that those who took nicotinamide developed fewer new cases of skin cancer compared with those who did not.

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Using these records, the research team reviewed the outcomes of 33,833 veterans who received baseline treatment with 500 milligrams of nicotinamide twice daily for more than 30 days.

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Among those studied, 12,287 patients had taken nicotinamide, while 21,479 had not.

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The researchers found a 14% overall decrease in skin cancer risk among nicotinamide users.

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