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nocebo

[ noh-see-boh ]

noun

  1. an inactive substance or a real medication that produces unpleasant or worsening symptoms in a patient or research participant because the person expects negative effects. Compare placebo ( def 1 ).
  2. a negative symptom experienced by a person with such expectations.


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Word History and Origins

Origin of nocebo1

1960–65; Latin nocēbō “I shall be harmful”; patterned after placebo

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Example Sentences

If someone feels ignored or belittled, they may experience a nocebo effect.

People also reported higher pain intensity on the “capsaicin” skin, an expected nocebo effect.

Brain stimulation affected neural pathways that were already thought to be involved in the placebo and nocebo effects.

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