- the failure of chromosomes to separate and segregate into daughter cells at division.
Origin of nondisjunction
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- the failure of paired homologous chromosomes to move to opposite poles of the cell during meiosis
- The failure of one or more pairs of chromosomes to separate at the miotic stage of karyokinesis, with the result that both chromosomes are carried to one daughter cell and none to the other.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.