Actually, the issue of plural vs. singular is orthogonal to the dilemma she wants to pose.
And that brings up another question about those bacterial targets, the ones that are so orthogonal to human cellular pathways.
In the first place, each of these figures may be conceived as an orthogonal projection of a closed plane-faced polyhedron.
Velocities in linkages were determined by orthogonal components transferred from link to link.
The involutes are “orthogonal trajectories” of the tangents to the common evolute.