The last may give an extreme anemia, indistinguishable from pernicious anemia.
In pernicious anemia they are always greatly diminished, and an increase should exclude the diagnosis of this disease.
It occurs in well-marked cases of pernicious anemia and leukemia, and, much less commonly, in very severe symptomatic anemias.
Pathologically, normoblasts occur in severe symptomatic anemia, leukemia, and pernicious anemia.
While always present in pernicious anemia, they are often difficult to find.
Megaloblasts are found in pernicious anemia, and with extreme rarity in any other condition.
As in pernicious anemia, the leukocytes are normal or decreased in number, with a relative increase of lymphocytes.
They occur most abundantly in malaria, leukemia, and pernicious anemia.
The color index is most significant in chlorosis and pernicious anemia.
It is sometimes associated with the blood-picture of pernicious anemia.
pernicious anemia n.
A severe form of anemia most often affecting older adults, caused by failure of the stomach to absorb vitamin B12 and characterized by abnormally large red blood cells, gastrointestinal disturbances, and lesions of the spinal cord. Also called Addison's anemia, malignant anemia.