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[pree-di-spohz] /ˌpri dɪˈspoʊz/
verb (used with object), predisposed, predisposing.
to give an inclination or tendency to beforehand; make susceptible:
Genetic factors may predispose human beings to certain metabolic diseases.
to render subject, susceptible, or liable:
The evidence predisposes him to public censure.
to dispose beforehand.
Archaic. to dispose of beforehand, as in a will, legacy, or the like.
verb (used without object), predisposed, predisposing.
to give or furnish a tendency or inclination:
an underground job that predisposes to lung infection.
Origin of predispose
First recorded in 1640-50; pre- + dispose
Related forms
predisposal, noun
[pree-di-spoh-zid-lee, -spohzd-] /ˌpri dɪˈspoʊ zɪd li, -ˈspoʊzd-/ (Show IPA),
predisposedness, noun
unpredisposed, adjective
unpredisposing, adjective
1. prearrange, prepare. 3. bias, incline. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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Examples from the Web for predisposed
Contemporary Examples
Historical Examples
  • On the other hand, the invert would have no influence on an individual who was not predisposed.

    The Sexual Question August Forel
  • Had she not been predisposed to think her father in the right?

    We Two Edna Lyall
  • Protection of children about to enter industry but predisposed to tuberculosis.

    Civics and Health William H. Allen
  • A man who has bought a house with nothing to pay for it is also predisposed to clutch.

    The House

    Eugene Field
  • But no girl gets "outed," as you call it, unless she's predisposed that way.

  • His appearance was striking, and predisposed all in his favor.

British Dictionary definitions for predisposed


verb (transitive)
often foll by to or towards. to incline or make (someone) susceptible to something beforehand
(mainly law) to dispose of (property, etc) beforehand; bequeath
Derived Forms
predisposal, noun
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for predisposed



1640s, "to put into a certain frame of mind," perhaps a back-formation from predisposition. Related: Predisposed; predisposing.

Online Etymology Dictionary, © 2010 Douglas Harper
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predisposed in Medicine

predispose pre·dis·pose (prē'dĭ-spōz')
v. pre·dis·posed, pre·dis·pos·ing, pre·dis·pos·es
To make susceptible, as to a disease.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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