- an act or instance of injecting an addictive drug intravenously.
- shootout(def 1).
Origin of shoot-up
First recorded in 1965–70; noun use of verb phrase shoot up
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
Examples from the Web for shoot-up
Yes, and we'll all hot-foot it to the burg of New York, and shoot-up the town!The Boy from the Ranch
Frank V. Webster