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softening of the brain

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noun Pathology.
  1. a softening of the cerebrum, caused by impairment of the blood supply; encephalomalacia.
  2. Informal. dementia associated with general paresis.
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Origin of softening of the brain

First recorded in 1825–35
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for softening of the brain

softening of the brain

noun
  1. an abnormal softening of the tissues of the cerebrum characterized by various degrees of mental impairment
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Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012