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spongy degeneration in Medicine

spongy degeneration

n.
  1. A rare, inherited, fatal brain disease of infancy characterized by the widespread loss of myelin from nerve sheaths and the presence of round empty spaces in the brain, giving it a spongelike appearance, and resulting in progressive paralysis, blindness, and megalencephaly.Canavan's disease
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.