"American Indian woman," 1630s, from Massachuset (Algonquian) squa "woman" (cf. also Narraganset squaws "woman"). "Over the years it has come to have a derogatory sense and is now considered offensive by many Native Americans" [Bright]. Widespread in U.S. place names, sometimes involving a translation of local American Indian words for "woman."
A woman, esp one's wife (1934+)