acetylcholine

American  

[uh-seet-l-koh-leen, uh-set-] / əˌsit lˈkoʊ lin, əˌsɛt- /

noun

1. Biochemistry. the acetic acid ester of choline, C 7 H 17 NO 3 , released and hydrolyzed during nerve conduction and causing muscle action by transmitting nerve impulses across synapses.

2. Pharmacology. this substance used in its chloride form in eye surgery. ACh

---

acetylcholine British  

/ ˌæsɪtaɪlˈkəʊliːn, -lɪn /

noun

1. a chemical substance secreted at the ends of many nerve fibres, esp in the autonomic nervous system, and responsible for the transmission of nervous impulses. Formula: CH 3 CO 2 (CH 2 ) 2 N (CH 3 ) 3 ⁺

---

acetylcholine Scientific  

/ ə-sēt′l-kō′lēn′ /

1. A substance that is released at the junction between neurons and skeletal muscle fibers, at the nerve endings of the parasympathetic nervous system, and across synapses in the central nervous system, where it acts as a neurotransmitter. Chemical formula: C ₇ H ₁₆ NO ₂ .

---

Other Word Forms

• acetylcholinic
  adjective

---

Etymology

Origin of acetylcholine

First recorded in 1905–10; acetyl + choline

---

Example Sentences

See Examples For:

acetylcholine

The results confirmed that acetylcholine plays an essential role in helping the brain adapt when circumstances change.

From Science Daily ● Jun. 8, 2026

While most released more acetylcholine, some small clusters of cells showed little change or even a decrease in activity.

From Science Daily ● Jun. 8, 2026

Caffeine blocks adenosine, a chemical that slows the activity of important brain messengers such as dopamine and acetylcholine.

From Science Daily ● May 13, 2026

When acetylcholine was introduced to lab-grown gut tissue containing EC cells, those cells responded by releasing serotonin.

From Science Daily ● Mar. 28, 2026

By this means a precise balance is struck and the body never builds up a dangerous amount of acetylcholine.

From "Silent Spring" by Rachel Carson

Random Word

Spin the wheel and learn a new word!

---