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a combining form meaning “place,” “local,” used in the formation of compound words:
topography; topology.
Also, especially before a vowel, top-.
Origin of topo-
combining form of Greek tópos place, commonplace Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2017.
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British Dictionary definitions for topo-


combining form
indicating place or region: topography, topology, toponym, topotype
Word Origin
from Greek topos a place, commonplace
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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topo- in Medicine

topo- or top-
Place; area: topoanesthesia.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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