Dictionary.com
Thesaurus.com

topoisomerase

American  
[tah-poh-ahy-sahm-uh-rays, -rayz] / ˌtɑ poʊˌaɪˈsɑm əˌreɪs, -ˌreɪz /

noun

  • topoisomerases
    plural
  1. an enzyme that corrects topological issues within DNA, such as supercoiling or entanglement.


Other Word Forms

Derived Forms

Inflected Forms

Nouns

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Marazzi says that he and his colleagues are working with a pharmaceutical company to organize a clinical trial to test whether blocking topoisomerase I is beneficial during sepsis.

From Science Magazine Apr. 28, 2016

The team’s findings suggest that topoisomerase I also helps orchestrate the immune system’s response to pathogen attacks.

From Science Magazine Apr. 28, 2016

Camptothecin is one of several topoisomerase I–inhibiting cancer drugs that have received approval from the Food and Drug Administration.

From Science Magazine Apr. 28, 2016

But he wants to see further animal studies to confirm that blocking topoisomerase is effective against other types of bacteria that more commonly cause sepsis in people.

From Science Magazine Apr. 28, 2016

Other noteworthy genes were APEX1, a multifunctional DNA repair enzyme, RFC1, replication factor C, and TOP2A, a DNA topoisomerase that controls the topologic states of DNA during transcription.

From Nature Nov. 15, 2011

These are resolved with the action of topoisomerases.

From Textbooks Jun. 9, 2022

Vocabulary.com logo
by dictionary.com

Look it up. Learn it forever.

Remember new words for good with VocabTrainer. Expand your vocabulary effortlessly with personalized learning tools that adapt to your goals.

Take me to Vocabulary.com