Marriage, the earthly way, is vicissitudinous, for everybody knows that anything is liable to happen to a man at large.
Mr. Lumley revived Nino (Nabucco) towards the close of his memorable and vicissitudinous management.
1560s, from Middle French vicissitude (14c.), from Latin vicissitudinem (nominative vicissitudo) "change," from vicissim "changeably, in turn," from vicis "a turn, change" (see vicarious). Related: Vicissitudes.