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creatinine

American  
[kree-at-n-een, -in] / kriˈæt nˌin, -ɪn /

noun

Biochemistry.
  1. a crystalline end product of creatine metabolism, C 4 H 7 N 3 O, occurring in urine, muscle, and blood.


creatinine British  
/ kriːˈætəˌniːn /

noun

  1. an anhydride of creatine that is abundant in muscle and excreted in the urine

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

creatinine Scientific  
/ krē-ătn-ēn′,-ĭn /
  1. A compound formed by the metabolism of creatine, found in muscle tissue and blood and normally excreted in the urine as a metabolic waste. Measurement of creatinine levels in the blood is used to evaluate kidney function. Chemical formula: C 4 H 7 N 3 O.


Etymology

Origin of creatinine

First recorded in 1850–55; from German Kreatinin, equivalent to kreatin creatine ( def. ) + -in -ine 2 ( def. )

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

When the protein albumin was measured in the urine, the average level for participants was 714 mg/gm of creatinine; levels of 30 or higher may be a sign of chronic kidney disease.

From Science Daily

ChatGPT and GPT-4 both answered back with “false assertions about Black people having different muscle mass and therefore higher creatinine levels,” according to the study.

From Seattle Times

Doctors at the hospital said Anirudh's kidneys were damaged, and that levels of creatinine - a waste product normally filtered out by the kidneys - were very high in his body.

From BBC

“The really new finding here is that these pig kidneys can clear enough creatinine to support an adult human,” Dr. Locke said.

From New York Times

But the U.A.B. study is the first to clearly show that the organs also filter creatinine, a byproduct of muscle contractions that must be removed from the blood.

From New York Times