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ketamine

American  
[kee-tuh-meen, -min] / ˈki təˌmin, -mɪn /

noun

Pharmacology.
  1. a synthetic nonbarbiturate general anesthetic, C 13 H 16 ClNO, used to induce anesthesia, alone or in combination, in surgical or diagnostic procedures of short duration; extensively used in veterinary medicine.


ketamine British  
/ ˈkɛtəmiːn /

noun

  1. a drug, chemically related to PCP, that is used in medicine as a general anaesthetic, being administered by injection; cyclohexylamine

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

ketamine Scientific  
/ kētə-mēn′ /
  1. A general anesthetic given intravenously or intramuscularly in the form of its hydrochloride salt, used especially for minor surgical procedures in which skeletal muscle relaxation is not required.


Etymology

Origin of ketamine

First recorded in 1965–70; ket- + -amine

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

They advertise treatment for Parkinson’s disease, post-stroke rehabilitation and many other conditions in addition to depression, Palamar said, adding that less than half mention risks associated with ketamine use.

From The Wall Street Journal • Mar. 17, 2026

But to Heifets’ surprise, many of the patients who reported improved mental health hadn’t received ketamine after all.

From Slate • Jan. 30, 2026

Chavez never met with Perry in person, but allowed Plasencia to continue the treatments despite knowing that Plasencia had “little” experience with ketamine treatments, according to his plea agreement.

From Los Angeles Times • Dec. 16, 2025

Tracey Gillies, executive medical director at NHS Lothian, said recent international studies suggested that the use of IV ketamine may be a cost-effective alternative to ECT.

From BBC • Jun. 22, 2025

“In an earlier study, we reported that for the analgesic ketamine, pain relief correlates negatively with how strongly connected two regions of the default mode network are before the drug’s administration,” explains Ueno.

From Science Daily • Dec. 3, 2024