sis

a suffix appearing in loanwords from Greek, where it was used to form from verbs abstract nouns of action, process, state, condition, etc.: thesis; aphesis.

Origin of -sis

From Greek

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2022

How to use sis in a sentence

According to big sis Kate, she can—if she leaves school behind.
Kate Moss Advises Younger Sister to Drop Out of School; Rachel Roy Wins Preliminary Hearing With Parent Company|The Fashion Beast Team|May 19, 2014|DAILY BEAST
The Brothers Rodham, you may recall, have their own distinguished history of causing headaches for Big Sis.
StopHillary Super PAC Goes After McAuliffe in Virginia Race|Michelle Cottle|September 18, 2013|DAILY BEAST
Put another way, having penetrated the SIS, he was then able to penetrate the CIA.
The Charmed Life of a Traitor|Harold Evans|November 6, 2009|DAILY BEAST
Sis Wolf, han' Sis Rabbit dat rickin'-cheer dar, 'kaze 't aint no one step fum her house ter mine.'
Nights With Uncle Remus|Joel Chandler Harris

He lugged in his arms, sis, a stove and a bed, And balanced a bureau right square on his head.
The Book of Humorous Verse|Various
I say, Dink, they both wanted to be remembered to you, and here's a note from Sis.
The Varmint|Owen Johnson
"She didn't drag me out, Sis; it was I who suggested it," interposed Horace.
The Nicest Girl in the School|Angela Brazil
Agamogenesis, a-gam-o-jen′e-sis, n. reproduction without sex, found among lower animals and in plants.
Chambers's Twentieth Century Dictionary (part 1 of 4: A-D)|Various

British Dictionary definitions for sis (1 of 3)

sis¹

/ (sɪs) /

noun

informal short for sister

British Dictionary definitions for sis (2 of 3)

sis²

sies

/ (sɪs, siːs) /

interjection

Southern African informal an exclamation of disgust

Word Origin for sis

Afrikaans, possibly from Khoi

British Dictionary definitions for sis (3 of 3)

SIS

abbreviation for

Also called: MI6 (in Britain) Secret Intelligence Service

(in New Zealand) Security Intelligence Service

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012