crossing over

American  

noun

Genetics.

1. the interchange of corresponding chromatid segments of homologous chromosomes with their linked genes.

---

crossing over British  

noun

1. biology the interchange of sections between pairing homologous chromosomes during the diplotene stage of meiosis. It results in the rearrangement of genes and produces variation in the inherited characteristics of the offspring See also linkage

---

crossing over Scientific  

/ krô′sĭng-ō′vər /

1. The exchange of genetic material between homologous chromosomes that occurs during meiosis and contributes to genetic variability.

---

Etymology

Origin of crossing over

First recorded in 1910–15

Example Sentences

See Examples For:

crossing over

The world’s largest wildlife crossing over the 101 Freeway in Agoura Hills is barreling toward a Dec. 2 completion date.

From Los Angeles Times ● Oct. 8, 2026

The artificial-intelligence build-out has officially begun crossing over to the world of junk bonds, where investors expect to be paid more for taking on bigger risks.

From MarketWatch ● Sep. 23, 2026

The first signs that a dog is crossing over into his senior years are often a graying muzzle, cloudier eyes or a slower gait.

From The Wall Street Journal ● Jul. 30, 2026

The band was a key part of a phenomenon known as Hallyu, which describes South Korean pop culture crossing over to the west.

From BBC ● Jan. 13, 2026

The canal ran parallel on the other side, with a bridge crossing over it at the far end of the street.

From "Code Name Kingfisher" by Liz Kessler