ATPase

American  

[ey-tee-pee-eys, -eyz] / ˈeɪˈtiˈpi eɪs, -eɪz /

noun

Biochemistry.

1. adenosine triphosphatase: any of several enzymes that catalyze the hydrolysis of ATP to ADP and phosphate.

---

ATPase British  

/ ˌeɪtiːˈpiːˌeɪz /

noun

1. adenosine triphosphatase; an enzyme that converts ATP to ADP

---

Etymology

Origin of ATPase

First recorded in 1945–50; ATP + -ase

Example Sentences

Using single-cell transcriptomics and functional testing, the team found that blocking this excessive lysosomal activity with a vacuolar ATPase inhibitor restored lysosomal health and improved the function of aging blood stem cells.

From Science Daily • May 12, 2026

Medications such as omeprazole, pantoprazole, and esomeprazole work by blocking the H+, K+, ATPase enzyme, also known as the proton pump.

From Science Daily • Feb. 26, 2026

Specifically, when ingested, the toxin targets the electrolyte pumps in the wall of the heart called the sodium potassium ATPase pump.

From Salon • Apr. 10, 2025

The Na+-K+ ATPase exists in two forms, depending on its orientation to the interior or exterior of the cell and its affinity for either sodium or potassium ions.

From Textbooks • Jun. 9, 2022

Describe how the role of the enzyme ATPase in the hydrolysis of ATP in a cell differs from a spark in the cylinder of an internal combustion engine.

From Textbooks • Jun. 9, 2022