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ligand

American  
[lahy-guhnd, lig-uhnd] / ˈlaɪ gənd, ˈlɪg ənd /

noun

  1. Biochemistry. a molecule, as an antibody, hormone, or drug, that binds to a receptor.

  2. Chemistry. a molecule, ion, or atom that is bonded to the central metal atom of a coordination compound.


ligand British  
/ ˈlaɪ-, ˈlɪɡənd /

noun

  1. chem an atom, molecule, radical, or ion forming a complex with a central atom

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of ligand

1945–50; < Latin ligandus, gerund of ligāre to bind, tie

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Both Ligand and Xoma are known as royalty aggregators for investing in drugs while they are in development and then, if they work out, collecting royalties from their sales.

From The Wall Street Journal • Apr. 27, 2026

Brought in by raider Dan Loeb, Ligand CEO John Higgins cut headcount from 365 to 18, where it remains today.

From Forbes • Jul. 1, 2015

Ligand and G protein are shown as a brown and blue ellipse, respectively.

From Nature • Feb. 13, 2013

Shares of Ligand Pharmaceuticals Inc, a small biotech firm that contributed to Kyprolis and would receive royalties from its sales, were up 1.8 percent at $17.85.

From Reuters • Jul. 20, 2012

Ligand Pharmaceuticals, which stands to receive royalties from sales of the drug, gained 7.7 percent.

From New York Times • Jun. 21, 2012

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