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pathogenesis

American  
[path-uh-jen-uh-sis] / ˌpæθ əˈdʒɛn ə sɪs /
Also pathogeny

noun

  1. the production and development of disease.


pathogenesis British  
/ pəˈθɒdʒɪnɪ, ˌpæθəˈdʒɛnɪsɪs, ˌpæθəʊdʒɪˈnɛtɪk /

noun

  1. the origin, development, and resultant effects of a disease

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of pathogenesis

From New Latin, dating back to 1875–80; see origin at patho-, -genesis

Explanation

The medical term pathogenesis means the source of a disease. Your doctor might guess that the pathogenesis of your ear infection was a bad cold that caused congestion and swelling. If you ask your doctor, "How did I get chickenpox?" you're asking about the pathogenesis of an illness that gave you an itchy rash and a high fever. The word stems from the Greek pathos, "suffering or disease," and genesis, "origin." In medical terms, pathogenesis lays out the biological progression of a disease from its origin to the symptoms it caused that sent you to your doctor's office.

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Vocabulary lists containing pathogenesis

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

"It was actually a really unexpected finding that suggests a totally new mechanism for Alzheimer's disease pathogenesis," said Huang.

From Science Daily Jun. 12, 2026

The results also align with earlier rodent studies showing that inadequate choline intake in mice can lead to obesity, metabolic problems and increased Alzheimer's disease pathogenesis.

From Science Daily Nov. 27, 2025

"We hope these advancements will enhance studies in biology, biophysics and biomedicine, where intricate interactions at the nanoscale are key to understanding cellular function in health and pathogenesis."

From Science Daily Nov. 26, 2024

These details can reveal how molecular interactions contribute to cellular functions, which is critical for advancing targeted therapies and understanding disease pathogenesis.

From Science Daily Nov. 26, 2024

The tracing of the direct and indirect relationships between these causes and the abnormal cerebral functioning upon which the disturbances of psychobiological adjustment seem to depend is the task of pathogenesis.

From A Psychiatric Milestone Bloomingdale Hospital Centenary, 1821-1921 by New York Hospital. Society

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